B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1

**Semantic type:** Neoplastic Process

**Definition:** A B-cell acute leukemia characterized by the presence of lymphoblasts that carry a translocation between the BCR gene on chromosome 22 and the ABL1 gene on chromosome 9. It results in the production of the p190 kd or p210 kd fusion protein. It has an unfavorable clinical outcome.

**Synonyms:** - Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive - B Acute Lymphoblastic Leukemia with BCR-ABL1 Fusion - B Acute Lymphoblastic Leukemia with BCR::ABL1 Fusion - B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR::ABL1 - B Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1 - B-Acute Lymphoblastic Leukemia with BCR-ABL1 Fusion - B-Acute Lymphoblastic Leukemia with BCR::ABL1 Fusion - B-Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1 - B-Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR::ABL1 - B-Cell Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1 - Philadelphia Positive Acute Lymphoblastic Leukemia - Philadelphia Positive Precursor Lymphoblastic Leukemia