t(11;17)(q13;q21)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A chromosomal translocation involving breakpoints within the q13 band on the long arm of chromosome 11 and the q21 band on the long arm of chromosome 17. This translocation may be associated with NUMA1-RARA fusion gene expression and acute promyelocytic leukemia or with the expression of various fusion genes (including FCHSD2-THRA, MBTD1-MYO7A, RNF169-CALCOCO2, RNF169-CBX1 and TPCN2-RARA) and solid tumors.