t(12;15)(p13;q25)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A chromosomal translocation involving breakpoints within the p13 band on the short arm of chromosome 12 and the q25 band on the long arm of chromosome 15. This rearrangement is associated with ETV6-NTRK3 fusion gene expression and congenital fibrosarcoma, congenital mesoblastic nephroma (cellular and mixed variants), and secretory ductal carcinoma of breast.