t(17;22)(q22;q13)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A cytogenetic abnormality that refers to a chromosomal translocation involving the long arm (q22) of chromosome 17 and the long arm (q13) of chromosome 22. It is associated with the expression of COL1A1/PDGFB fusions and most if not all cases of dermatofibrosarcoma protuberans (DFSP).