t(12;22)(p13;q11)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A chromosomal translocation involving breakpoints within the p13 band on the short arm of chromosome 12 and the q11 band on the long arm of chromosome 22. This rearrangement is associated with aberrant expression of the CCND2 gene and mantle cell lymphoma or MN1-ETV6 fusion gene expression and myeloid disorders.