Inactivating MLH1 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the MLH1 gene that either inhibits expression or results in the translation of an inactive DNA mismatch repair protein Mlh1 protein.

**Synonyms:** - Inactivating MLH1 Mutation - Loss of Function COCA2 Gene Mutation - Loss of Function HNPCC2 Gene Mutation - Loss of Function MLH1 Gene Mutation - Loss of Function MLH1 Mutation - Loss of Function MutL Homolog 1 Gene Mutation - Loss of Function MutL, E. coli, Homolog of, 1 Gene Mutation - MLH1 Gene Inactivation - MLH1 Loss of Function Gene Mutation - MLH1 Loss of Function Mutation - hMLH1 Mismatch Repair Gene Inactivation