Inactivating MSH6 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the MSH6 gene that either inhibits expression or results in the translation of an inactive DNA mismatch repair protein Msh6 protein.

**Synonyms:** - Inactivating MSH6 Mutation - Loss of Function HNPCC5 Gene Mutation - Loss of Function MSH6 Gene Mutation - Loss of Function MSH6 Mutation - Loss of Function MutS Homolog 6 Gene Mutation - Loss of Function MutS, E. coli, Homolog of, 6 Gene Mutation - MSH6 Gene Inactivation - MSH6 Loss of Function Gene Mutation - MSH6 Loss of Function Mutation - hMSH6 Mismatch Repair Gene Inactivation