Anaplastic Carcinoma Cell

**Semantic type:** Cell

**Definition:** A malignant epithelial cell, usually of large size, characterized by the lack of differentiation. Anaplastic carcinoma cells have large hyperchromatic nuclei and display marked variation in nuclear size and shape, and high mitotic rate. Atypical mitotic figures are often present.

**Synonyms:** - Anaplastic Malignant Epithelial Cell - Pleomorphic Carcinoma Cell - Pleomorphic Malignant Epithelial Cell