Small Lymphocytic Lymphoma with Immunoglobulin Heavy Chain Variable-Region Gene Somatic Hypermutation

**Semantic type:** Neoplastic Process

**Definition:** Small lymphocytic lymphoma characterized by the presence of somatic hypermutation within the immunoglobulin heavy chain gene variable region of neoplastic clones. Patients have a better prognosis as compared to those with unmutated immunoglobulin heavy chain gene variable region rearrangements.

**Synonyms:** - Postgerminal Center Small Lymphocytic Lymphoma - SLL with IGVH SH