Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. (NCI04)

**Synonyms:** - AG-858