Survivin Antigen

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** A tumor-associated antigen. Vaccination with survivin antigen may result in a cytotoxic T-cell response against survivin antigen-expressing tumor cells, resulting in decreased tumor cell proliferation and tumor cell death. Overexpressed in many tumors, endogenous survivin inhibits tumor cell apoptosis.