Ciprofloxacin

**Semantic type:** Antibiotic|Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. (NCI04)

**Synonyms:** - 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid - CIPROFLOXACIN - Cipro - Cipro - ciprofloxacin