Pancreatic Neuroendocrine Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** An aggressive high-grade carcinoma with neuroendocrine differentiation that arises from the islet cells of the pancreas. It is composed of malignant small or large cells. The mitotic count is more than 20 per 2 mm2 and/or the Ki-67 index is more than 20%.

**Synonyms:** - CARCINOMA, ISLET CELL, MALIGNANT - High Grade Pancreatic Neuroendocrine Carcinoma - High-Grade Pancreatic Neuroendocrine Carcinoma - Islet Cell Cancer - Islet Cell Carcinoma - Islet Cell Carcinoma - Islet cell carcinoma - Malignant Islet Cell Tumor - Malignant Pancreatic Endocrine Tumor - PanNEC - Pancreatic Endocrine Carcinoma - Pancreatic NEC - Pancreatic Neuroendocrine Cancer - Poorly Differentiated Neuroendocrine Neoplasm - Poorly Differentiated Pancreatic Endocrine Carcinoma - islet cell cancer - pancreatic endocrine cancer