Autoimmune Lymphoproliferative Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autoimmune hematologic disorder characterized by autoimmune hemolytic anemia, thrombocytopenia, lymphadenopathy, hepatomegaly and splenomegaly. Patients are at an increased risk of developing Hodgkin and non-Hodgkin lymphomas.

**Synonyms:** - ALPS - Autoimmune Lymphoproliferative Syndrome (ALPS) - Canale-Smith Syndrome