Intramedullary Route of Administration

**Semantic type:** Functional Concept

**Definition:** Administration of a drug within the marrow cavity of a bone. The essential premise for intraosseous administration is a functioning medullary cavity. The route is considered reasonably safe and permits rapid achievement of satisfactory plasma concentrations of therapeutic agent. The route is used for blood transfusion or fluid therapy when other routes are awkward, as in neonates.

**Synonyms:** - I-MEDUL - I-MEDUL - INTRAMEDULLARY - INTRAMEDULLARY - INTRAMEDULLARY - Intramedullary - Intramedullary