5-Hydroxypicolinaldehyde Thiosemicarbazone

**Semantic type:** Pharmacologic Substance

**Definition:** A thiosemicarbazone antimetabolite. A derivative of 5-hydroxypicolinaldehyde, 5-HP inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. (NCI04)

**Synonyms:** - 5-HP - 5-HYDROXYPYRIDINE-2-CARBOXALDEHYDE THIOSEMICARBAZONE - 5-Hydroxypyridine-2-carboxaldehyde Thiosemicarbazone