Nitric Oxide Synthase, Endothelial

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Nitric oxide synthase, endothelial (1203 aa, ~133 kDa) is encoded by the human NOS3 gene. This protein plays a role in the modulation of vascular smooth muscle relaxation, VEGF-induced angiogenesis and blood coagulation.

**Synonyms:** - CNOS - Constitutive NOS - EC 1.14.13.39 - EC-NOS - ECNOS - ENOS - Endothelial NOS - Endothelial Nitric Oxide Synthase - Endothelial Nitric Oxide Synthase 3 - NOS Type III - NOS3 - NOSIII - Nitric Oxide Synthase 3 - cNOS - eNOS