Selective Estrogen Receptor Modulator CC-8490

**Semantic type:** Pharmacologic Substance

**Definition:** A benzopyran with potential antineoplastic activity. CC-8490 acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. (NCI04)

**Synonyms:** - CC-8490 - CC-8490 - SPC8490