Axitinib

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect.

**Synonyms:** - AG 013736 - AG-013736 - AG-013736 - AG013736 - AXITINIB - Inlyta - N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide - axitinib