Elongation Factor 1B1

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Encoded by human EEF1B1 Gene (EF1Beta/EF1Delta Family), 224-aa 24.6-kDa Elongation Factor 1B1 is a subunit of heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma or alpha/delta/gamma subunits). Composed of an alpha subunit nucleotide binding domain and a beta/gamma subunit nucleotide exchange complex, Elongation Factor 1 is responsible for delivery of aminoacyl tRNAs to the ribosome. The homologous guanine nucleotide exchange factor EF-1-beta and EF-1-delta subunits stimulate GDP/GTP exchange bound to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. (NCI)

**Synonyms:** - EEF1B1 - EF-1-Beta1 - Elongation Factor-1-Beta1 - Eukaryotic Translation Elongation Factor 1 Beta 1