Therapeutic Cortisone

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A corticosteroid with potent glucocorticoid activity. Therapeutic cortisone is the inactive precursor molecule of the active hormone cortisol, which is the hydroxylation product of cortisone by 11-beta-steroid dehydrogenase. Cortisol increases blood pressure and blood sugar levels, and suppresses the immune system, therefore cortisone is used to treat allergies or inflammation.

**Synonyms:** - 17,21-Dihydroxypregn-4-ene-3,11,20-trione - CORTISONE - Cortisone - Cortisone