Acral Lentiginous Melanoma

**Semantic type:** Neoplastic Process

**Definition:** A form of melanoma occurring most often on the plantar, palmar, subungual, and periungual skin. It presents as a pigmented macular lesion with irregular borders. Morphologically, it consists of atypical spindled and dendritic melanocytes. The epidermis is often hyperplastic and there is pagetoid infiltration of the epidermis by anaplastic cells.

**Synonyms:** - Acral Lentiginous Malignant Melanoma - Acral lentiginous melanoma, malignant