Testicular Germ Cell Neoplasia In Situ

**Semantic type:** Neoplastic Process

**Definition:** A non-invasive lesion of the testis, characterized by the presence of malignant large germ cells with abundant cytoplasm in the seminiferous tubules. It may be associated with undescended or atrophic testis and infertility. The vast majority of cases progress to invasive germ cell tumors.

**Synonyms:** - GCNIS - Gonocytoma In Situ - IGCNU - Intratubular malignant germ cells - Testicular Intraepithelial Neoplasia - Testicular Intratubular Germ Cell Neoplasia - Testicular Intratubular Germ Cell Neoplasia of Unclassified Type - Testicular Intratubular Germ Cell Neoplasia of the Unclassified Type - Testicular Intratubular Germ Cell Neoplasia, Unclassified - Testicular Intratubular Germ Cell Neoplasia, Unclassified