Histamine Degradation

**Semantic type:** Physiologic Function

**Definition:** Histamine Degradation consists of conjugation, transport, oxidation, or enzymatic breakdown of a decarboxylation product of histidine (histamine), found particularly in mast cells and basophils, and involved in capillary dilation and permeability; blood pressure decrease; smooth muscle contraction; gastric secretion; heart rate acceleration; immediate hypersensitivity; and central neurotransmission.