Ameloblastic Fibrosarcoma

**Semantic type:** Neoplastic Process

**Definition:** A locally aggressive malignant neoplasm arising from odontogenic tissue. It occurs in the mandible and less often in the maxilla. It is characterized by the presence of a malignant connective tissue component and a benign epithelial component. The frequency of distal metastases is low.

**Synonyms:** - AFS - Ameloblastic fibrosarcoma - Ameloblastic sarcoma