Myeloid Leukemia Associated with Down Syndrome

**Semantic type:** Neoplastic Process

**Definition:** Acute myeloid leukemia or myelodysplastic syndrome occurring in children with Down syndrome. The acute myeloid leukemia is usually an acute megakaryoblastic leukemia, and is associated with GATA1 gene mutation.

**Synonyms:** - AML Occurring in Children with Down Syndrome - Acute Myeloid Leukemia Occurring in Children with Down syndrome - Acute Myeloid Leukemia with GATA1 Mutations - MLDS - Myeloid leukemia associated with Down Syndrome