Toluene Diisocyanate

**Semantic type:** Hazardous or Poisonous Substance

**Definition:** A synthetic mixture of the 2,4- and 2,6-isomers is a volatile, colorless to pale yellow liquid that is soluble in many organic solvents. These isomers are used primarily in the synthesis of polyurethane foams. When heated to decomposition, toluene diisocyanate emits toxic fumes of cyanides and nitrogen oxides. Exposure of humans to toluene diisocyanate causes tissue irritation, especially to the mucous membranes, and can produce severe respiratory problems. These isomers are reasonably anticipated to be human carcinogens. (NCI05)

**Synonyms:** - 2,4-Tolylene Diisocyanate - 4-Methyl-m-phenylene Diisocyanate - Nacconate 100 - TDI - TOLUENE DIISOCYANATE (MIXED ISOMERS) - UN 2078