Inversion Mutation Abnormality

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A structural change in genomic DNA where the 5' to 3' order of a nucleotide sequence is completely reversed to the 3' to 5' order relative to its adjacent sequences. This inversion is termed either pericentric, if it includes the centromere of a chromosome, or pancentric, if it excludes the centromere. An inversion mutation abnormality may be heritable or occur somatically.

**Synonyms:** - Inversion - Inversion - Inversion - Inversion - Inversion - Inversion - Inversion Mutation - Inversion NOS - inv