CYP2C9*3 Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYP2C9*3 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*3 protein. The CYP2C9*3 allele exhibits a clinically-relevant SNP (c.1075A>C) in exon 7 that results in an I359L coding change. This alteration in protein sequence decreases the enzymatic activity of the cytochrome P450 2C9*3 protein.

**Synonyms:** - CYP2C9*3 - CYP2C9, I359L - CYP2C9, c.1075A>C - Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*3 Allele