CYP2D6*10 Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYP2D6*10 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*10 protein. The CYP2D6*10 allele exhibits a clinically-relevant SNP (g.100C>T) that results in a P34S coding change. This alteration decreases the enzymatic activity of the cytochrome P450 2D6*10 protein.

**Synonyms:** - CYP2D6 NG_008376.4:g.[5119C>T;7870=;9200G>C] - CYP2D6*10 - CYP2D6, P34S, S486T - CYP2D6J - Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*10 Allele