CYP2D6*5 Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYP2D6*5 allele is a variant form of the CYP2D6 wild-type allele. The CYP2D6*5 allele is a result of deletion of the entire CYP2D6 gene. Thus, the CYP2D6*5 allele does not encode a cytochrome P450 2D6 protein. This is the basis of the poor metabolizer phenotype in individuals who carry this allele.

**Synonyms:** - CYP2D6 Deleted - CYP2D6*5 - CYP2D6, del - CYP2D6D - Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*5 Allele