Lobular Cancerization

**Semantic type:** Finding

**Definition:** Lobular Cancerization (or cancerization of lobules, COL) is the presence in a lobule of ductal carcinoma in situ (DCIS) tumor cells with preservation of the normal lobular pattern. It appears to represents a variation in the growth pattern of DCIS, not secondary extension of DCIS into a lobule.

**Synonyms:** - COL - Cancerization of a Lobule