CYP2C9*16 Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYP2C9*16 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*16 protein. The CYP2C9*16 allele exhibits a clinically-relevant SNP (c.895A>G) that results in a T299A coding change. This alteration in protein sequence decreases the in vivo enzymatic activity of the cytochrome P450 2C9*16 protein.

**Synonyms:** - CYP2C9*16 - CYP2C9, T299A - CYP2C9, c.895A>G - Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*16 Allele