Albendazole

**Semantic type:** Pharmacologic Substance

**Definition:** A broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death. Albendazole is used in the treatment of dog and pork tapeworm-causing diseases, including hydatid disease and neurocysticercosis. Albendazole may also be used to treat a variety of other roundworm infections. (NCI05)

**Synonyms:** - ALBENDAZOLE - Albenza - Bilutac - Carbamic Acid,(5-(Propylthio)-1H-benzimidazol-2-yl)-, Methyl Ester - Proftril - SKF 62979 - Zentel