Amlexanox

**Semantic type:** Pharmacologic Substance

**Definition:** An anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers.

**Synonyms:** - 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic Acid - 5H-(1)Benzopyrano(2,3-b)pyridine-3-carboxylic Acid, 2-Amino-7-(1-methylethyl)-5-oxo- - AA 673 - AA-673 - AMLEXANOX - Aphthasol - CHX 3673 - Solfa