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C47565Level 5

Iobenguane Sulfate I-131

**Semantic type:** Pharmacologic Substance

**Definition:** The sulfate salt form of iobenguane, an iodine-131 labeled aralkylguanidine norepinephrine analogue used as a diagnostic imaging tracer. Iobenguane is structurally related to guanethidine and norepinephrine. This agent, functioning as a false substrate of norepinephrine, is taken up and localized in the granules of pre-synaptic adrenergic neurons, thus making this compound useful for the imaging of neuroendocrine tissues and tumors.

**Synonyms:** - Guanidine,((3-(iodo-131I)phenyl)methyl)-, Sulfate(2:1) - IOBENGUANE SULFATE I-131

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