Penicillin G Benzathine

**Semantic type:** Antibiotic|Pharmacologic Substance

**Definition:** The long-acting benzathine salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G benzathine binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

**Synonyms:** - Benzathine Benzylpenicillin Tetrahydrate - Benzylpenicillin Benzathine Hydrate - Bicillin - PENICILLIN G BENZATHINE - Permapen