Proparacaine Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** The hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.

**Synonyms:** - 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate Monohydrochloride - Alcaine - Benzoic Acid, 3-Amino-4-propoxy-, 2-(diethylamino)ethyl Ester, Hydrochloride - Benzoic Acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl Ester, Hydrochloride - Keracaine - Ophthetic - PROPARACAINE HYDROCHLORIDE - Proxymetacaine Hydrochloride