Pseudoephedrine Sulfate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The sulfate salt form of pseudoephedrine, a phenethylamine and a diastereomer of ephedrine with sympathomimetic property. Pseudoephedrine sulfate displaces norepinephrine from storage vesicles in presynaptic neurones, thereby releasing norepinephrine into the neuronal synapses where it stimulates primarily alpha-adrenergic receptors. It also has weak direct agonist activity at alpha- and beta- adrenergic receptors. Receptor stimulation results in vasoconstriction and decreases nasal and sinus congestion.

**Synonyms:** - Afrin - Afrinol - Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, (alphaS)-,Sulfate (2:1) (salt) - D-Isoephedrine Sulfate - PSEUDOEPHEDRINE SULFATE