Sulfamethoxazole

**Semantic type:** Pharmacologic Substance

**Definition:** A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.

**Synonyms:** - Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)- - Gamazole - Metoxal - Radonil - SULFAMETHOXAZOLE - Sulfanilamide, N'-(5-methyl-3-isoxazolyl)- - Sulfisomezole