Poly [ADP-Ribose] Polymerase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Poly [ADP-ribose] polymerase 1 (1013aa, ~113 kDa) is encoded by the human PARP1 gene. This protein is involved in poly ADP-ribosylation and in the regulation of various cellular processes such as differentiation, proliferation, tumor transformation, and recovery from DNA damage.

**Synonyms:** - ADP-Ribosyltransferase - ADP-Ribosyltransferase Diphtheria Toxin-Like 1 - ADP-Ribosyltransferase NAD(+) - ADPRT 1 - ARTD1 - EC 2.4.2.30 - NAD(+) ADP-Ribosyltransferase 1 - PARP - PARP - PARP-1 - PARP-1 - PARP1 - Poly (ADP Ribose) Polymerase 1 - Poly(ADP Ribose) Polymerase - Poly(ADP Ribose) Polymerase 1 - Poly(ADP-Ribose) Synthetase - Poly(ADP-Ribosyl)Transferase - Poly[ADP-Ribose] Synthase 1 - poly (ADP-ribose) polymerase - poly(ADP-ribose) polymerase-1