Primary Sclerosing Cholangitis

**Semantic type:** Disease or Syndrome

**Definition:** A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

**Synonyms:** - PSC - Sclerosing Cholangitis