Bone Ewing Sarcoma

**Semantic type:** Neoplastic Process

**Definition:** A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. Fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.

**Synonyms:** - Bone Ewing's Sarcoma - Ewing Sarcoma of Bone - Ewing Sarcoma of Bone - Ewing's Sarcoma of Bone - Ewing's Sarcoma, Osseous - Osseous Ewing's Sarcoma - Osseous Ewing's Tumor - Skeletal Ewing's Sarcoma - Skeletal Ewing's Tumor