Adenovector Encoding MDA7

**Semantic type:** Pharmacologic Substance

**Definition:** A nonreplicating adenoviral vector (adenovector) encoding the melanoma differentiation-associated 7 gene (MDA7) with potential antineoplastic activity. After intratumoral injection and adenovector-mediated gene transfer of MDA7 into tumor cells, the expressed MDA7 transgene may inhibit tumor cell proliferation and induce tumor cell apoptosis.

**Synonyms:** - Ad-MDA-7 - INGN241