Allogeneic GM-CSF-Secreting Breast Cancer Vaccine

**Semantic type:** Cell|Immunologic Factor|Pharmacologic Substance

**Definition:** An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.

**Synonyms:** - GM-CSF BREAST VAC - GM-CSF-secreting breast tumor vaccine