Autologous Dendritic Cell-Allogeneic Melanoma Tumor Cell Lysate Vaccine

**Semantic type:** Cell|Immunologic Factor|Pharmacologic Substance

**Definition:** A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T-cell and antibody responses to melanoma cells bearing shared melanoma antigens such as MelanA/MART-1, gp100, MAGE3, resulting in tumor cell lysis.

**Synonyms:** - Allogeneic Melanoma Cell-Loaded Dendritic Cell Vaccine - IDD-3