pan-HER Kinase Inhibitor AC480

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. (NCI05)

**Synonyms:** - AC480 - AC480 - BMS-599626 - BMS-599626 - BMS-599626