GM.CD40L Cell Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A cell-based vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage colony-stimulating factor (GM-CSF) and CD40-ligand (CD40L) genes. Upon administration, this vaccine may stimulate an anti-tumoral dendritic cell-mediated host immune response. (NCI05)

**Synonyms:** - GM.CD40L