Recombinant Human Papillomavirus Bivalent Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with potential immunoprotective and antineoplastic properties. Upon administration, HPV 16/18 L1 virus-like particle/ASO4 vaccine may generate humoral and cellular immunity against HPV types-16 and -18 antigens, thereby preventing cervical infection upon exposure to HPV types 16 and 18. In addition, this agent may stimulate an antitumoral cellular immune response against cervical cancer associated with HPV infection.

**Synonyms:** - Cervarix - Cervarix - GSK-580299 - HPV 16/18 L1 VLP/AS04 VAC - HPV-16/18 VLP/AS04 Vaccine - Human Papillomavirus 16/18 L1 Virus-Like Particle/AS04 Vaccine - Human Papillomavirus Bivalent Types 16 and 18 Vaccine, Recombinant - Human Papillomavirus Vaccine L1 16,18 - Human Papillomavirus Vaccine, L1 Type 16, 18 - Recombinant HPV Bivalent Vaccine - human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine