Veltuzumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody directed against the CD20 antigen with potential antineoplastic activity. Following binding, veltuzumab triggers complement-dependent cell lysis (CDCL) and antibody-dependent cell-mediated cytotoxicity (ADCC) in cells that overexpress CD20. CD20 antigen is a hydrophobic transmembrane protein located on pre-B and mature B lymphocytes.

**Synonyms:** - Anti-CD20 Monoclonal Antibody hA20 - HCD20 - IMMU-106 - IMMU-106 - MoAb hA20 - Monoclonal Antibody hA20 - VELTUZUMAB - hA20 - veltuzumab